Breast tissue density has also been shown to be a major determinant of interval cancer, which is defined as cancer that becomes apparent clinically, usually because of a lump, between routine mammographic screenings. Retrospective studies have shown that 15 percent to 30 percent of interval cancers appear on the original screening mammogram that was initially interpreted as negative. The other 70 percent to 85 percent are not seen mammographically, even in retrospect ... read more
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